ABSTRACT
Soap is a cosmetic product in common use during this pandemic period. It enables barrier gestures to be carried out. Capable of preventing pathology (COVID-19), it should, therefore, be marketed under a drug status. If we consider the history of soap, we realize the complexity of its status. Depending on the period, it has been considered as a hygiene product and/or as an excipient or an active ingredient allowing the production of a drug or cosmetic making it possible to treat both scabies and burns, to carry out purges or to put at the point of preparations to soften or whiten hands or to lengthen eyelashes. The use of the term “soap”, being extremely overused, the establishment of regulations to clarify this situation is essential. © 2020 Elsevier Masson SAS
ABSTRACT
OBJECTIVE: Soap has been used by humankind since ancient times and was probably already known to the Sumerians. It is a fatty acid salt obtained from the reaction of a strong base with a fatty substance of animal (tallow) or plant origin (oil). This reaction is called saponification. Syndets, on the other hand, are much more recent and have been in use for about a century. In the case of liquid syndets, they are mainly alkyl sulphates and their derivatives alkyl ether sulphates while isethionates and sarcosinates are more commonly found in solid syndets. Synthetic soaps and detergents are surfactants and, as such, they have detergent properties. The way soap works accounts for its antimicrobial properties. Thanks to its amphiphilic structure, it is able to interact with the lipid membranes of microorganisms (viruses, bacteria, etc.) and inactivate them. In this coronavirus pandemic period, health authorities worldwide recommend hand washing with soap and water. We therefore wanted to provide a summary of the chemical characteristics and applications of soaps, on the one hand, and synthetic detergents, on the other. Soap is not the only product used for hand hygiene and, given the current situation, alternatives are complex and varied.